Peptide drugs are becoming increasingly popular due to their high affinity and specificity for their biological target, plus their low toxicity. Lead optimisation can further enhance their pharmacological properties. Lipidation/PEGylation, side-chain substitution, macrocyclisation, truncation, N-methylation and alanine scanning are techniques often used to achieve this outcome. Modpep can perform a comprehensive SAR study for your lead compound in a timely manner.
